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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
12.5 DPC

12 matching records from 12 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Dct  dopachrome tautomerase   (Synonyms: TRP2, TRP-2, tyrosinase-related protein-2, Tyrp2, Tyrp-2)
Results  Reference
1J:160209 Buac K, Xu M, Cronin J, Weeraratna AT, Hewitt SM, Pavan WJ, NRG1 / ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation. Pigment Cell Melanoma Res. 2009 Dec;22(6):773-84
1J:119015 Kellerer S, Schreiner S, Stolt CC, Scholz S, Bosl MR, Wegner M, Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence. Development. 2006 Aug;133(15):2875-86
1*J:84057 Lee HO, Levorse JM, Shin MK, The endothelin receptor-B is required for the migration of neural crest-derived melanocyte and enteric neuron precursors. Dev Biol. 2003 Jul 1;259(1):162-75
1J:241206 Marathe HG, Watkins-Chow DE, Weider M, Hoffmann A, Mehta G, Trivedi A, Aras S, Basuroy T, Mehrotra A, Bennett DC, Wegner M, Pavan WJ, de la Serna IL, BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation. Nucleic Acids Res. 2017 Jun 20;45(11):6442-6458
1*J:71587 Potterf SB, Mollaaghababa R, Hou L, Southard-Smith EM, Hornyak TJ, Arnheiter H, Pavan WJ, Analysis of sox10 function in neural crest-derived melanocyte development: sox10-dependent transcriptional control of dopachrome tautomerase. Dev Biol. 2001 Sep 15;237(2):245-57
1*J:84755 Rao C, Foernzler D, Loftus SK, Liu S, McPherson JD, Jungers KA, Apte SS, Pavan WJ, Beier DR, A defect in a novel ADAMTS family member is the cause of the belted white-spotting mutation. Development. 2003 Oct;130(19):4665-72
1J:124679 Schreiner S, Cossais F, Fischer K, Scholz S, Bosl MR, Holtmann B, Sendtner M, Wegner M, Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages. Development. 2007 Sep;134(18):3271-81
1*J:194281 Silver DL, Leeds KE, Hwang HW, Miller EE, Pavan WJ, The EJC component Magoh regulates proliferation and expansion of neural crest-derived melanocytes. Dev Biol. 2013 Mar 15;375(2):172-81
1*J:69377 Wehrle-Haller B, Meller M, Weston JA, Analysis of melanocyte precursors in Nf1 mutants reveals that MGF/KIT signaling promotes directed cell migration independent of its function in cell survival. Dev Biol. 2001 Apr 15;232(2):471-83
1*J:34586 Wehrle-Haller B, Morrison-Graham K, Weston JA, Ectopic c-kit expression affects the fate of melanocyte precursors in Patch mutant embryos. Dev Biol. 1996 Aug 1;177(2):463-74
1*J:40215 Wehrle-Haller B, Weston JA, Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the lateral neural crest migration pathway. Development. 1995 Mar;121(3):731-42
1*J:55577 Wehrle-Haller B, Weston JA, Altered cell-surface targeting of stem cell factor causes loss of melanocyte precursors in Steel17H mutant mice. Dev Biol. 1999 Jun 1;210(1):71-86

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory